Relation between Helicobacter Pylori infection and Irritable Bowel Syndrome

Abstract

Background: Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal disorder. The association of Helicobacter pylori(H. pylori) infection with IBS still remains controversial. Objective: The objective of this study is to determine the rate of H. pylori infection among patients with IBS through the detection of H. pyloriStool Antigen Teesttitre (SAT) Materials &Methods :,This study will be performed on 80 patient attended GIT out patient clinic of sohag university hospital from 6/2017to 3/2018 will be classified into: 1-controle group (20patients)who do not fulfill criteria for diagnosis of irritable bowel syndrome 2-Affected group(60patients) who fulfill criteria for diagnosis of irritable bowel syndrome Those groups will be classified according to severity Also the affected groups will be classified according to subtypes All patents underlying the following: (1) history will be taken including: (2)Full clinical examination (3) Laboratory investigations Fasting blood glucose level,HBA1C renal function .liver function, complete blood counting Abdominal ultrasonography H.pylori stool antigen test titr (SAT) Results: Comparison was done among all types of IBS as regard H.Pylori SAT revealed constipation predominant cases have the highest number(33%) of H.Pylori SAT positive cases while lowest number of cases(4%) were unclassified, Comparison was done among all grades of IBS as regard H. Pylori SAT revealed grade 3 cases the highest number of H. Pylori SAT positive cases, lowest number of cases were grade1 Conclusion: In this study revealed positive relationship between H . Pylori infection and irritable bowel syndrome as regard types of irritable bowel syndrome, the incidence of H. Pylori infection was more with constipation predominant patients and as regard severity of irritable bowel syndrome , H . Pylori infection more common in grade 3.