Relating damped oscillations to sustained limit cycles describing real and ideal batch fermentation processes

Abstract

A batch fermentation model is presented in which the specific growth rate and yield functions are chosen such that sustained oscillations in both the cell and substrate concentration occur. This phenomenon is shown to be a Hopf bifurcation in the underlying system of non-linear ordinary differential equations which comprises the model. It is shown that for oscillations in the substrate concentration to occur it is necessary for the yield term to depend on both the cell and substrate levels.