Related factors of anemia in premature infants

Abstract

Objective To investigate the related factors and preventive strategies of anemia in premature infants. Methods A total of 1 093 preterm infants, who were born in our hospital between January and December 2016, were included as the subjects in the study and underwent hemoglobin test. According to the hemoglobin levels, all the subjects were divided into the anemia group and control group. The clinical data of the two groups of preterm infants and pregnant women were collected, including the gender, days of age, birth weight and gestational age. The history of anemia or hemolysis in pregnant women, the incidence of neonatal infection or neonatal asphyxia, and the blood collection volume of neonates were recorded. The influencing factors of anemia in the preterm infants were determined by Logistic regression analysis. Results Of the 1 093 preterm infants, 293 developed anemia and the incidence of anemia in preterm infants was 26.8% (293/1 093). The clinical data showed that the birth weight in the anemia group significantly decreased compared with that in the control group ; and the maternal history of anemia or hemolysis, neonatal blood collection volume>10 ml/kg, neonatal infection and neonatal asphyxia in the anemia group were significantly higher than those in the control group (all P 10 ml/kg and neonatal asphyxia were the risk factors of anemia in premature infants (all P <0.05 ). Conclusion The anemia in premature infants is related to low birth weight of neonates , maternal history of anemia or hemolysis, neonatal infection, neonatal blood collection volume>10 ml/kg and neonatal asphyxia. Key words: Infant, premature; Anemia; Risk factors; Regression analysis