Abstract
The objective of the study: to characterize the cases of tuberculosis relapses with lesion in urogenital organs.Subjects and methods. Out of 140 case histories of patients with urogenital tuberculosis (UGTB; tuberculosis of the urinary and male reproductive system), registered for follow-up by the phthisiourologist, all files of patients with tuberculosis relapses were picked up, totally, there were 13 of them.Results. Men prevailed among cases of relapses (61.5%). Patients at the age of 30-50 years old made 46.1%, and 53.9% were 51 years old and above. In the first episode of tuberculosis, lesions of the genitourinary system were observed in 53.9% of patients, bacterial excretion was found in 38.5%. On the average, the relapse developed in 9.1 years after successful cure of the first episode of tuberculosis: after respiratory tuberculosis – in 5.6 years and after UGTB – in 12.3 years. In 3 (23.1%) patients with relapse, mycobacteriuria was documented, in 1 of them, drug resistance (to streptomycin and isoniazid) was detected. In general, in the relapse of tuberculosis with urogenital lesions, the kidneys were most often (69.2%) affected. The treatment of relapse was effective in 12 out of 13 patients. During chemotherapy of tuberculosis, 3 (23.1%) patients developed toxic and allergic reactions that required treatment interruption or cancellation of the drug.
Highlights
Out of 140 case histories of patients with urogenital tuberculosis (UGTB; tuberculosis of the urinary and male reproductive registered for follow-up by the phthisiourologist, Men prevailed among cases of relapses (61.5%)
All files of p Patients at atients with tuberculosis relapses were picked up, totally, there were the age of 30-50 years old made 46.1%, and 53.9% were 51 years old 13 of them. and above
In the first episode of tuberculosis, lesions of the genitourinary system were observed in 53.9% of patients, bacterial excretion was found in 38.5%
Summary
Цель исследования: охарактеризовать случаи рецидива туберкулеза с поражением урогенитальных органов. Из 140 амбулаторных карт больных урогенитальным туберкулезом (УГТ; туберкулез мочевой и мужской половой системы), находящихся на диспансерном учете у фтизиоуролога, выбраны все карты больных с рецидивом туберкулеза, их оказалось 13. Среди больных с рецидивом преобладали мужчины (61,5%). При первом эпизоде туберкулеза поражение органов мочеполовой системы было у 53,9% пациентов, бактериовыделение установлено у 38,5%. Средний срок рецидива после успешного излечения первого эпизода туберкулеза составил 9,1 года: после туберкулеза органов дыхания - в среднем 5,6 года; после УГТ - в среднем 12,3 года. У 3 (23,1%) больных с рецидивом зафиксирована микобактериурия, у 1 из них выявлена лекарственная устойчивость микобактерий туберкулеза (к стрептомицину и изониазиду). У 3 (23,1%) больных во время химиотерапии туберкулеза были токсико-аллергические реакции, требовавшие перерыва в лечении или отмены препаратов.
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