Relapses and remissions of hypokalaemic periodic paralysis and multiple sclerosis in the same patient

Abstract

Hypokalaemic periodic paralysis (HOKPP, OMIM 170400) is a are dominantly inherited disorder, which in approximately 70% of ases results from mutation in the CACNA1S calcium channel gene. It resents clinically with attacks of flaccid limb muscle weakness [1]. ultiple sclerosis (MS) is a more common inflammatory disease of he central nervous system characterized by episodic or progressive eurological disability. The case of a patient in whom exacerbations and remissions f both diseases were intermingled, is described. This resulted in ome difficulty in diagnosing the disease that presented later. To ur knowledge, only two such cases have been previously described 2,3].