Abstract
BackgroundPapillary Urothelial Neoplasm of Low Malignant Potential (PUNLMP) are exceptionally rare in the first decade of life (mostly if multifocal) and there is a lack of standardized recommendations for the pediatric age.Case presentationWe describe the case of a 9-year-old boy with a diagnosis of PUNLMP, who underwent to cystoscopic lesion removal and later to endoscopic lesion removal and intra-bladder Mitomycin-c (MMC) instillations for relapsed disease. Follow-up investigations at five years showed disease negativity.ConclusionsIntra-bladder MMC instillation may allow obtaining the complete remission with bladder-sparing for paediatric patients with a high-risk relapsed PUNLMP.
Highlights
Papillary Urothelial Neoplasm of Low Malignant Potential (PUNLMP) are exceptionally rare in the first decade of life and there is a lack of standardized recommendations for the pediatric age
Urothelial bladder neoplasms are extremely rare in the first decades of life, with an incidence of 0.1–0.4% and less than 35 cases described in children below ten years of age [1,2,3]
Case presentation We describe the case of an otherwise healthy 9-y-old boy with a bladder neoplasm, whose clinical history started a year before years with macroscopic haematuria
Summary
Papillary Urothelial Neoplasm of Low Malignant Potential (PUNLMP) are exceptionally rare in the first decade of life (mostly if multifocal) and there is a lack of standardized recommendations for the pediatric age. Full list of author information is available at the end of the article We performed a close follow-up with renal function, renal and urinary ultrasound, urodynamic evaluation, which was found normal.
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