Abstract

Sodium chloride treatment triggered the accumulation of (p)ppGpp in the Bacillus subtilis relA+ strain IS58 as well as in its relaxed counterpart IS56. Besides this relA-independent (p)ppGpp induction the GTP and ATP pools decreased dramatically. In previous papers we found a direct correlation between (p)ppGpp accumulation and stress protein induction. In B. subtilis relA the (p)ppGpp accumulation was accompanied by the induction of general stress proteins whose synthesis rates were also enhanced by heat stress, amino acid limitation or oxygen starvation. Specific heat shock proteins were not induced by salt stress. We suggest that these general stress proteins are induced under non-growing conditions in general.

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