Abstract
Introduction: There are differences between patients with early and established rheumatoid arthritis (RA) that can condition quality of life and prognosis of the disease. Material and methods: Descriptive, cross-sectional study in a cohort of RA patients with regular follow-up visits in two third-level hospitals. A questionnaire with epidemiological, clinical, laboratory and radiographic variables was completed, in addition to physical examination. Patients were divided into 3 groups: 0 to 12 months, 13 to 60 months and more than 60 months of disease duration. Results: 330 patients were included, with mean disease duration of 108.19±91.17 months. Patients with less than 12 months of disease duration have a BMI of less than 25 more frequently (50% vs. 24.9%, p 0.037), they also have a higher average SJC (3.20±3.6 vs. 1.64±2.7, p 0.034), TJC (3.53±4.13 vs. 1.7±2.77, p 0.015) and pain VAS (28.93±30.14 vs. 15.09 ± 19.79, p 0.011). Meanwhile, patients with more than 60 months disease duration are older (53.08±12 vs. 48.23±14, p 0.002), have a higher incidence of erosions (39% vs. 21%, p 0.004) and osteoporosis (23.5% vs. 12.9%, p 0.023) and a lower average TJC (1.49±2.5 vs. 2.28±3.3, p 0.018). Conclusion: Patients with shorter disease duration have higher average activity indexes. Patients with longer disease duration have a higher frequency of erosive disease and osteoporosis but lower average tender joint counts.
Highlights
There are differences between patients with early and established rheumatoid arthritis (RA) that can condition quality of life and prognosis of the disease
Patients were divided into 3 groups: 0 to 12 months, 13 to 60 months and more than 60 months of disease duration
Patients with more than 60 months disease duration are older (53.08 ± 12 vs. 48.23 ± 14, p 0.002), have a higher incidence of erosions (39% vs. 21%, p 0.004) and osteoporosis (23.5% vs. 12.9%, p 0.023) and a lower average TJC (1.49 ± 2.5 vs. 2.28 ± 3.3, p 0.018)
Summary
Vannia Valinotti[1], Lourdes Román[1], Astrid Paats[1 ], Romina Glizt[2], Armando Mallorquín[2], Gabriela Ávila-Pedretti[2 ], Sonia Cabrera-Villalba[1,2]. Resultados: Fueron incluidos 330 pacientes, con una duración media de enfermedad de 108,19 ± 91.17 meses. Los pacientes con una duración de enfermedad menor a 12 meses presentan un IMC menor a 25 con mayor frecuencia (50% vs 24.9%, p 0.037), asimismo tenían un mayor promedio de NAT (3.20 ± 3.6 vs 1.64 ± 2.7, p 0.034), NAD (3.53 ± 4.13 vs 1.7 ± 2.77 p 0.015) y de EVA dolor (28.93 ± 30.14 vs 15.09 ± 19.79, p 0.011). En el grupo mayor a 60 meses, los pacientes son mayores (53.08 ±12 vs 48.23 ± 14, p 0.002), tienen erosiones (39% vs 21%, p 0.004) y osteoporosis con mayor frecuencia (23,5% vs 12,9%, p 0.023) y menor número de NAD (1.49 ± 2.5 vs 2.28 ± 3.3, p 0.018). Los pacientes con mayor duración de enfermedad tienen mayor frecuencia de enfermedad erosiva y osteoporosis, pero menores recuentos de articulaciones dolorosas
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