Abstract
Short poly‐l‐lactic acid (PLLA) microfibers have been produced in order to disperse them into the gelatin solution and enable injection in the tissue defect prior to gel formation. Two methods for fabrication of loose fibers with submicrometric dimensions are presented in this paper. One is based on manufacturing electrospun meshes and subsequent milling (PLLA‐ES) and the other involves projection of a PLLA solution into a high turbulent non‐solvent medium (PLLA‐HT). Composites produced with PLLA‐ES show a compression Young's modulus from 2.65 kPa for the pure gelatin to 6.69 kPa for the composite with 1.5% PLLA‐ES fibers. The new injectable gelatin–fiber composites are not cytotoxic.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.