Reinfection of SARS CoV-2 in patients with relapse of symptoms after clinical recovery: A Case Series

Abstract

Background: It has been more than a year, and still, we are battling with a novel coronavirus (SARS-COV-2). Initially, the interim guidelines by the World health organization (WHO) stated that infection ranges from asymptomatic to critical life-threatening pneumonia with the symptomatology of fever, cough and breathing difficulty. Objectives: To observe the reinfection of SARS CoV-2 in patients with relapse of symptoms after clinical recovery. Materials and methods: Three cases were observed during the isolation period. Reverse transcription polymerase chain reaction (RT-PCR) and severity of similar symptoms in the fourth week from the onset was monitored. Results: All the three patients had health care exposure, and which pointed us towards health care associated reinfection could be a possible cause of step-up in the symptom severity. Conclusion: Reinfection by SARS CoV-2 can be considered in patients with relapse of symptoms after clinical recovery after natural infections.