Abstract

.Controlling and ultimately ending tuberculosis (TB) as a public health scourge will require a multifaceted and comprehensive approach involving the intensification of public health efforts, including scaling-up the delivery of current diagnostic, preventive, and therapeutic tools. However, a critically important element in the effort to end TB is an accelerated biomedical research effort to address the many unanswered questions about the disease process itself and to develop improved and innovative countermeasures. An intensive effort toward these research goals will facilitate the achievement of the aspirational goal of ending TB.

Highlights

  • The first World Health Organization (WHO) Global Ministerial Conference on Ending TB in the Sustainable Development Era: A Multisectoral Response (Moscow, November 16–17, 2017) was an historical event that brought attention to the compelling need to reassess the global effort to end this historic scourge

  • More than 2 billion people are estimated to be latently infected with Mycobacterium tuberculosis (Mtb), and TB is the leading cause of death among infectious diseases and one of the top 10 causes of death worldwide

  • About 490,000 of the new cases were multidrug-resistant TB (MDR-TB), with 6.2% of those cases identified as extensively drug-resistant TB (XDR-TB).[2]

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Summary

Introduction

The first World Health Organization (WHO) Global Ministerial Conference on Ending TB in the Sustainable Development Era: A Multisectoral Response (Moscow, November 16–17, 2017) was an historical event that brought attention to the compelling need to reassess the global effort to end this historic scourge.

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