Abstract
As a subset of T cells,regulatory T cells (Tregs) exert an immunosuppressive effect through direct and indirect cell-cell contact,and play a pivotal role in the development of immunologic selftolerance.Atopic dermatitis (AD) is a chronic,recurrent and inflammatory skin disease with a complex pathogenesis.Although Th2 cells have been the focus for research on the pathogenesis of atopic dermatitis,recent studies have shown the important roles of regulatory T cells in atopic dermatitis.To learn the changes of Tregs in patients with atopic dermatitis from childhood to adulthood will help to understand their roles in the pathogenesis of,and to develop new therapeutic strategies for,atopic dermatitis. Key words: Dermatitis, atopic; T-lymphocytes, regulatory; Immunity
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