Abstract
Bacteria response to their environment by producing some compounds which are used in cosmetic and pharmaceutical applications. Some probiotics can regulate immune response and modulate the symptoms of several diseases. Bacteria affect skin response to skin care products. Bacteria are thought to play an important role in acne incidence, skin moisture, and nutrient metabolism, but only a few studies have focused on the extracts of Lactobacillus plantarum in skin care. In this study, we identified that L. plantarum-GMNL6 enhanced collagen synthesis and the gene expression of serine palmitoyltransferase small subunit A. Meanwhile, L. plantarum-GMNL6 reduced the melanin synthesis, the biofilm of Staphylococcus aureus, and the proliferation of Cutibacterium acnes. Information from clinical observation during the ointment for external face use in people displayed that the syndromes of skin moisture, skin color, spots, wrinkles, UV spots, and porphyrins were improved. The diversification of human skin microbiomes was affected by smearing the face of volunteers with L. plantarum-GMNL6. Understanding the potential mechanisms of the action of L. plantarum-GMNL6 in dermatologic conditions promotes the development of care products.
Highlights
Some products of bacteria with anti-oxidative activity have been show to play an important role in skin care
In order to find out the optimal probiotics, the various potentially probiotics were treated with HS68 cells by using collagen synthesis and the gene expression of serine palmitoyltransferase small subunit A (SPTSSA) assays
L. plantarum-GMNL6 had the best ability to stimulate the gene expression of SPTSSA compared with other probiotics (Fig. 1B)
Summary
Some products of bacteria with anti-oxidative activity have been show to play an important role in skin care. Bacteria can produce some compounds in response to environmental stress. These compounds of bacteria are generally used in medicine, cosmetics, even in sports [1]. Some probiotics have immunomodulatory activities and modulate the symptoms of several diseases [2]. Some specific probiotic strains, including Bifidobacterium, Saccharomyces, Enterococcus, Bacillus, and Lactobacillus, have been demonstrated for health benefits [5]. Some probiotics is able to serve as a potential care products. Probiotics such as lactobacillus have been demonstrated to modulator skin symptoms [8].
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