Abstract
As the crucial member of noncoding RNA family, there is increasing evidence that long noncoding RNA has participated in numerous physiological and pathological processes of organisms. HOXA distal transcript antisense RNA is a long noncoding transcript located at the 5′ tip of HOXA. According to research reports, the up-regulation of HOTTIP is closely associated with occurrence and progression of multiple digestive system cancers and promotes the carcinogenesis. The regulatory effect of long noncoding RNA HOXA distal transcript antisense in digestive system neoplasms will be summarized in this article. Key words: Digestive system neoplasms; Prognosis; Review; Long noncoding RNA; HOXA distal transcript antisense RNA
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