Abstract
In recent years, research on posttranslational proteins has received widespread attention. In the toolbox of chemical biology targeting protein prenylation, we report a sequential azidation-selenylation reaction and a click reaction that can target posttranslational prenyl modified proteins. Inspired from PROTAC technique, we achieved the degradation of posttranslational prenyl modified RAS in the A549 cell line.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
