Regulation of Phosphate and Mineral Metabolism

Abstract

I. Renal Handling of Phosphate.- The Adaptive System of the Tubular Transport of Phosphate.- Nephron Sites of Adaptation to Changes in Dietary Phosphate.- Phosphate Reabsorption in the Distal Convoluted Tubule.- Metabolic Abnormalities Underlying the Pathogenesis of Vitamin D Resistant Rickets (VDRR).- Relationship Between Plasma Phosphate and Renal Handling of Phosphate: Studies with Low Phosphate Diet and Nicotinamide.- Protein Phosphorylation in Proximal Tubular Brush-Border Membranes.- Possible Relationship of Gluconeogenesis to Modulation of Phosphate Transport in the Proximal Tubule.- Interactions Between Phosphate Transport and Oxidative Metabolism in the Rabbit Proximal Tubule.- Abnormal Tubular Pi Adaptation to Dietary Pi Restriction and Decreased Calcium Reabsorption in X-Linked Hypophosphatemic (HYP) Mice.- Renal Pi Transport in Young Growing and Adult Rats: Comparative Studies in Brush Border Membrane Vesicles (BBMV) and in Whole Kidney.- Difference in Renal Tubular Transport Effects of 1-34 and 1-84 Parathyroid Hormone (PTH).- 1,25-Dihydroxycholecalciferol (calcitriol): Effect on Phosphate (PO4) Absorption by Isolated Pars Recta.- In Vivo and In Vitro Effects of Vitamin D3 (1,25-(OH)2 D3) on the Uptake of Phosphate by Isolated Chick Kidney Cells.- Potassium Imbalance and Phosphate Renal Handling: A Micropuncture Study.- Renal Handling of Divalent Cations and Phosphate During Water Immersion in the Awake Dog.- The Effects of Calcium on ADH Action in Cortical Collecting Tubules Perfused In Vitro.- II. Phosphate Metabolism in Health and Disease.- The Creatine-Creatine Phosphate Shuttle for Energy Transport-Compartmentation of Creatine Phosphokinase in Muscle.- Hormonal Regulation of Phosphate Transport in the Differentiating Chick Small Intestine.- Measurement of Intracellular Inorganic Phosphate in Human Blood Red Cells, Leucocytes and Platelets.- Intracellular Inorganic Phosphate and ATP Levels in Human Blood Erythrocytes, Leucocytes and Platelets in Normal Subjects and in Diseases Associated with Altered Phosphate Metabolism.- Prevention of Phsophate Induced Progression of Experimental Uremia by 3-Phosphocitric Acid.- Phosphate Hemeostasis in Cimetidine Treated Uremic Dogs.- Regulation of Phosphate Excretion by the Diseased Kidney. The Intrinsic Proximal Tubular Adaptation.- Parathyroid Hormone Resistance in Renal Allograft Recipients.- III. Hypophosphatemia and Phosphate Depletion.- Models of Hypophosphatemia and Phosphate Depletion.- Effect of Phosphate Depletion on the Myocardium.- Hypophosphatemia and Osteoblast Function in Human Bone Disease.- Hypophosphatemia and Glucose Intolerance.- Acute Hypophosphatemia During Total Parenteral Nutrition in Man: Its Effects on Muscle Cell Composition.- Proximal Renal Tubular Acidosis and Hypophosphatemia Induced by Arginine.- Cardiac Function and Metabolism in Phosphorous Depleted Dogs - Effects of Hormonal Stimulation.- Circulatory Response to Pressor Agents in Phosphorous Depletion.- Phosphate and Vanadate Reduce the Efficiency of the Chemo-Mechanical Energy Transformation in Cardiac Muscle.- Effects of Hypophosphatemia on Pulmonary Muscle Performance.- Experimental Alcoholism Induces Phosphorus and Magnesium Deficiency in Skeletal Muscle.- Defective Hormonal Stimulation of Isolated Hepatocytes in Phosphorus Depleted Rats.- Should Hypophosphatemia Be Treated?.- IV. Topics on Vitamin V Metabolism.- Development and Application of an Exchange Assay for 1,25-Dihydroxy-Vitamin D3.- Effects of Systemic pH on Calcium Regulating Hormones and Bones.- Inherited and Acquired Disorders of Vitamin D Metabolism.- The Molecular Nature of 1,25-(OH)2-D3-Induced Calcium-Binding Protein Biosynthesis in the Rat.- Effects of 1,25-Dihydroxy Vitamin D3 in Patients with Early Renal Failure.- Increased serum 1,25-(OH)2-Vitamin D Concentrations Fail to Affect Serum or urine Phosphate in Humans.- Adrenergic Blackade May Inhibit the Increase in Plasma 1,25-(OH)2-Vitamin D During Phosphate Deprivation in the Rat.- V. Topics on Bone Metabolism.- Regulation of Osteoblast Activity and the Osteoblast-Osteocyte Transformation.- Role of Monocytes in Bone Resorption.- Coupling Factor.- Glutamine: A New Metabolic Substrate.- Evolution of Renal Osteodystrophy in Patients Treated by Continuous Ambulatory Peritoneal Dialysis.- VI. Calcium Metabolism.- Measurements of Intracellular Free Ca++.- The Regulation of Intracellular Calcium.- Calcium as Intracellular Messenger in Hormone Action.- Effects of Diuretics on Calcium Metabolism.- Effects of Chlorothiazide Administration and Dietary Calcium Restriction on Parathyroid Function, Vitamin D Metabolism and Intestinal Calcium Absorption in the Rat.- Calcium Fluxes Across Membranes Isolated from Small Intestinal Epithelium.- VII.Parathyroid Hormone Metabolism and Its Extraskeletal Effects.- The Parathyroid Hormone Molecule: Biological Implications of Structure.- Functional Properties of Parathyroid Hormone Receptors in Kidney and Bone.- Assessment of Biologically Active Parathyroid Hormone in Hyperparathyroid Man.- Effect of Parathyroid Hormone on Phospholipid Metabolism.- Effects of Parathyroid Hormone on Glomerular Ultrafiltration in the Rat.- Regulation Mechanisms of the Renal Phosphate Handling in Renal Failure - What is the Role of PTH?.- Interactions Between Liver and Parathyroid Hormone.- Parathyroid Hormone and the Heart.- Vascular Effects of Parathyroid Hormone (PTH).- Role of PTH, Metabolic Factors and Other Hormones in Extra-Renal Acid Buffering.- Effect of Parathyroid Hormone on the Isolated Papillary Muscle of the Rat Heart.- Effect of Parathyroid Hormone on Rat Enterocyte Na Transport in Vitro.- Comparison of Propranolol and Atenolol in the Control of Hyperparathyroidism in Uremia.- Effects of Oral Cimetidine on Parathyroid Hormone and Calcitonin Plasma Levels in Uremic Patients.