Abstract
Ginger (Zingiber officinae Roscoe) is a flowering plant in family Zingiberaceae whose roots is widely used as an ingredient in both cooking and East Asian traditional medicine.
Highlights
Ginger (Zingiber officinae Roscoe) is a flowering plant in family Zingiberaceae whose roots is widely used as an ingredient in both cooking and East Asian traditional medicine
We found that Ginger Extract (Gin C) inhibited contractions of murine uterus longitudinal smooth muscle by inhibition of voltage-dependent L-type Ca2+ channels (VDCCL)
This finding suggests that Gin C may inhibit mouse uterine smooth muscle contractions by inhibiting VDCCL and/or VDCCT strongly
Summary
Ginger (Zingiber officinae Roscoe) is a flowering plant in family Zingiberaceae whose roots is widely used as an ingredient in both cooking and East Asian traditional medicine. It has been reported that ginger can regulate contractility of uterine, gastrointestinal (GI) tract, and airway smooth muscle. Rat uterine muscle tone and spontaneous contractions can be enhanced by ginger extract [5]. Such enhancing effect on the contraction is produced by activation of voltage-dependent L-type Ca2+ channels (VDCCL) and release of Ca2+ from sarcoplasmic reticulum [5]. Other reports have suggested similar enhancing effects of ginger extract on rabbit uterine smooth muscle tone and its spontaneous contractions [6]. Regulatory effects of ginger on contractility of uterine, gastrointestinal (GI) tract, and airway smooth muscle have been reported [5,6,11]
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