Abstract

<div>Food intake is regulated by complex hypothalamic neuronal systems</div><div>originally identified as hunger and satiety centers. The search for the underlying</div><div>mechanisms led to the discovery of several central orexigenic and anorexigenic</div><div>peptides. The present chapter summarizes the current knowledge about the role of</div><div>classical hypothalamic neuropeptides such NPY/AgRP, POMC/CART, melanocortin,</div><div>and orexin system, as well as several new central signals such as AMPK, ncRNA, and</div><div>autophagy involved in the regulation of appetite and food intake.</div>

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