Regulation of Cyclin D1 Degradation by Ubiquitin-Specific Protease 27X Is Critical for Cancer Cell Proliferation and Tumor Growth.

Swati Venkat, Amanda Zunic + Show 3 more

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https://doi.org/10.1158/1541-7786.mcr-22-0259

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Journal: Molecular cancer research : MCR	Publication Date: Aug 24, 2022
Citations: 6	License type: cc-by

Abstract

As a deubiquitinating enzyme, USP27X is a druggable target. Our study illuminates new avenues for therapeutic intervention in CCND1-driven cancers.

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