Abstract
Hormonal control of the phosphorylase system, metabolism of radioactive substrates, and trehalose synthesis were examined in the fat body. Fat body phosphorylase is maximally activated within 10 min after being exposed to corpus cardiacum extracts and is sensitive to very low concentrations of the extract. The concentration of phosphorylase-activating factor in the gland appears to be related to changes in glycogen content during oögenesis. The hormone elicits an accelerated rate of trehalose release, an increase in oxygen consumption, and a decrease in the respiratory quotient. The rate of oxidation of glycose to CO 2 is decreased, but that of acetate and palmitate are both increased in fat body incubated with corpus cardiacum extracts. A hypothesis considering the new metabolic effects of the hormone suggests that its regulatory action is effective at a number of different sites.
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