Abstract

Non-equilibrium sensing and taxis of catalytically active biocolloids is crucial for understanding physiological processes and designing artificial nano- and microrobotic systems. We have demonstrated that the localization of a G-quadruplex based DNAzyme is biased to a zone where it shows higher peroxidase activity (lively area). The image shows how by diminishing the effect of inhibitors (Hg2+, symbolized by Halloween ghosts) by arresting them with thymidine-containing oligonucleotides, the activity of DNAzymes can be retained with concurrent migration from the catalytically inhibited region (deadly area). More information can be found in the Research Article by S. Maiti et al.

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