Regrettable Omission

Abstract

I would like to draw your readers’ attention to the fact that the article by Iwanaga et al titled “Regulation of alternative splicing of caspase-2 through an intracellular signaling pathway in response to pro-apoptotic stimuli”1Iwanaga N. Kamachi M. Aratake K. Izumi Y. Hiroaki I. Fumiko T. et al.Regulation of alternative splicing of caspase-2 through an intracellular signaling pathway in response to pro-apoptotic stimuli.J Lab Clin Med. 2005; 145: 105-110Google Scholar did not cite previous work from our group, although that article would appear to build on our earlier observations. We had shown that etoposide was able to trigger caspase-2 alternative mRNA splicing in U937 cells, among other cells.2Solier S. Lansiaux A. Logette E. Wu J. Soret J. Tazi J. et al.Topoisomerase I and II inhibitors control caspase-2 pre-messenger RNA splicing in human cells.Mol Cancer Res. 2004; 2: 53-61Google Scholar, 3Wotawa A. Solier S. Logette E. Solary E. Corcos L. Differential influence of etoposide on two caspase-2 mRNA isoforms in leukemic cells.Cancer Lett. 2002; 185: 181-189Google Scholar Iwanaga et al reported the same observations using the exact same PCR approach (and the same primers) and similar kinetics with RNA from etoposide-treated U937 cells. Of course, we are pleased to have our results confirmed by another group. However, even though these authors brought in additional information, we feel that they should have at least mentioned the previously published results, and we are quite disappointed by the omission. I would like to draw your readers’ attention to the fact that the article by Iwanaga et al titled “Regulation of alternative splicing of caspase-2 through an intracellular signaling pathway in response to pro-apoptotic stimuli”1Iwanaga N. Kamachi M. Aratake K. Izumi Y. Hiroaki I. Fumiko T. et al.Regulation of alternative splicing of caspase-2 through an intracellular signaling pathway in response to pro-apoptotic stimuli.J Lab Clin Med. 2005; 145: 105-110Google Scholar did not cite previous work from our group, although that article would appear to build on our earlier observations. We had shown that etoposide was able to trigger caspase-2 alternative mRNA splicing in U937 cells, among other cells.2Solier S. Lansiaux A. Logette E. Wu J. Soret J. Tazi J. et al.Topoisomerase I and II inhibitors control caspase-2 pre-messenger RNA splicing in human cells.Mol Cancer Res. 2004; 2: 53-61Google Scholar, 3Wotawa A. Solier S. Logette E. Solary E. Corcos L. Differential influence of etoposide on two caspase-2 mRNA isoforms in leukemic cells.Cancer Lett. 2002; 185: 181-189Google Scholar Iwanaga et al reported the same observations using the exact same PCR approach (and the same primers) and similar kinetics with RNA from etoposide-treated U937 cells. Of course, we are pleased to have our results confirmed by another group. However, even though these authors brought in additional information, we feel that they should have at least mentioned the previously published results, and we are quite disappointed by the omission.