Abstract
Background It is generally acknowledged that the 17-segment AHA model provides a suitable approximation for mapping the results of X-ray angiography onto myocardial anatomy in a consistent way in the absence of a more exact method. In practice, coronary anatomy varies from patient to patient which is acknowledged as the main limitation of the AHA model. The aim of this study was to establish whether the generation of a patient-specific coronary artery to perfusion segment map improved diagnosis of myocardial ischaemia.
Highlights
It is generally acknowledged that the 17-segment AHA model provides a suitable approximation for mapping the results of X-ray angiography onto myocardial anatomy in a consistent way in the absence of a more exact method
In this retrospective sub-study with the data from the CE-MARC trial (Greenwood et al, Lancet, 2012) an 18-patient sample was selected where the image quality of the magnetic resonance angiography (MRA) data allowed for a reliable manual coronary tree annotation
For a total of 54 coronary arteries eight cases (15%) were diagnosed incorrectly with the AHA model, while only five cases (9%) were diagnosed incorrectly with perfusion analysis based on patient-specific coronary supply territories (Table 1)
Summary
Registration of coronary MRA to DCE-MRI myocardial perfusion series improves diagnostic accuracy through the computation of patient-specific coronary supply territories: a CE-MARC sub-study. Constantine Zakkaroff2*, Aleksandra Radjenovic, John D Biglands, Sven Plein, John P Greenwood, Derek R Magee. From 17th Annual SCMR Scientific Sessions New Orleans, LA, USA. From 17th Annual SCMR Scientific Sessions New Orleans, LA, USA. 16-19 January 2014
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