Abstract
Organolithium chemistry is broadly integrated and widely applied in studies that bridge inorganic, physical, organic, and theoretical chemistry.1 Reactions with organolithium species as reagents, reactants, or intermediates are so well established that organolithiums are the most widely used organometallics in contemporary organic chemistry. Deprotonative lithiations are commonly used to generate enolates, ylides, and dipole-stabilized, localized sp2 or sp or delocalized carbanions as reactive intermediates for diverse applications.2 A sequence in which a proton on a tetrahedral carbon is replaced by a substituent begins with removal of a proton from 1 to give the formally sp3 organolithium 2. Reaction of 2 with an electrophile subsequently provides 3.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
