Abstract
The efficiency and selectivity of annulation reactions are often difficult to control in the presence of multiple potential reactive centers, like in the case of allylic sulfur ylides (ASY). Here, we describe a novel base mediated [3+3] benzannulation of ASY and readily available alkynones, which accomplishes the regioselective formation of multisubstituted thioanisoles, highly sought after chemical scaffolds. A new reactivity pattern of ASY has been unearthed, where it acted as both a 3C component and sulfur source in benzannulation. Use of a widely available base, operational simplicity and broad substrate scope are the additional salient features of the conversion.
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