Regioselective and stereospecific synthesis of functionalized 3,4-dihydro-2H-1,4-thiazines by catalyst-free [3 + 3] annulation of pyridinium 1,4-zwitterionic thiolates and aziridines

Abstract

An efficient route to 3,4-dihydro-2H-1,4-thiazines was developed though [3 + 3] annulation of pyridinium 1,4-zwitterionic thiolates and aziridines under catalyst-free conditions.