Abstract

Background Numerous studies have shown that placing the left ventricular (LV) pacing lead in the latest contracting region (mechanically dyssynchronous) or the latest activated region (electrically dyssynchronous) of the LV improves patient response to Cardiac Resynchronization Therapy (CRT). However, no studies have examined electrical and mechanical dyssynchrony in the same patients to examine electrical-mechanical coupling. We hypothesized that the region of latest mechanical contraction would correspond to the region of latest electrical activation but the time between mechanical and electrical activation would vary between patients.

Highlights

  • Regions of latest mechanical contraction correspond to regions of latest electrical activation: an electro-mechanical coupling study in patients undergoing cardiac resynchronization therapy

  • Numerous studies have shown that placing the left ventricular (LV) pacing lead in the latest contracting region or the latest activated region of the LV improves patient response to Cardiac Resynchronization Therapy (CRT)

  • We hypothesized that the region of latest mechanical contraction would correspond to the region of latest electrical activation but the time between mechanical and electrical activation would vary between patients

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Summary

Open Access

Regions of latest mechanical contraction correspond to regions of latest electrical activation: an electro-mechanical coupling study in patients undergoing cardiac resynchronization therapy. Jonathan D Suever1*, Gregory Hartlage, Patrick Magrath, Michael Lloyd, John Oshinski. From 17th Annual SCMR Scientific Sessions New Orleans, LA, USA. From 17th Annual SCMR Scientific Sessions New Orleans, LA, USA. 16-19 January 2014

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