Abstract
Methods We assessed regional variation in T1 in the septum of patients with no left ventricular pathology. An adjunct phantom study was performed to assess whether location closer to a surface coil affected T1. Main study: Retrospective. 40 patients whose cardiac MRI showed no left ventricular disease were identified. Patients were imaged on a Siemens Avanto 1.5T scanner with a 32-channel cardiac coil. All patients had a 4-chamber TI scout approximately 12 minutes post injection of 0.14 mmol/kg gad-BOPTA. QMASS (Medis, NL) was used to generate T1 maps and measurements obtained in small regions of interest throughout the septum. Basal, middle third, and apical regions were evaluated in all 40; a subset of 15 patients
Highlights
T1 mapping is a newer technique for characterizing the myocardium, regional variations in the healthy left ventricle are not yet fully explored, complicating interpretation of observed pathologic differences
Adjunct study: TI scout and MOLLI images of a liquid phantom phantom were obtained at several simulated heart rates
Mid-ventricle was different from 3⁄4 (p=0.008) and apical septum (p
Summary
T1 mapping is a newer technique for characterizing the myocardium, regional variations in the healthy left ventricle are not yet fully explored, complicating interpretation of observed pathologic differences. Regional variations in T1 in the healthy left ventricle Background T1 mapping is a newer technique for characterizing the myocardium, regional variations in the healthy left ventricle are not yet fully explored, complicating interpretation of observed pathologic differences. Methods We assessed regional variation in T1 in the septum of patients with no left ventricular pathology.
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