Abstract

Direct corrections of regional differential tritium autoabsorption in quantitative autoradiography of the central nervous system are made using chloroform extraction of brain sections from rats receiving tritiated 2-deoxyglucose in vivo. Fifty-two regional quenching coefficients varied from 30% in gray structures to 100% in white structures. These data may be used to correct for regional quenching of tritium emissions in autoradiographic studies of rat brain.

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