Regional myoglobin concentration in the myocardium of the dog.

Abstract

It has been demonstrated previously that chronic hypoxia leads to an increase in myoglobin concentration. Evidence of differences in [Formula: see text] and blood flow in deep and superficial layers of cardiac muscle suggest that there might be a corresponding difference in myoglobin concentration in the myocardium. Results showed an even distribution of myoglobin concentration in inner and outer layers of the left ventricular wall, right ventricle, and septum, suggesting that [Formula: see text] in inner layers of the left ventricular wall is not sufficiently diminished to stimulate an increase in myoglobin concentration.