Abstract
SummaryRegional lung function was studied in 12 children without cardiopulmonary disease. 133Xe was used as a tracer and external detectors were employed. Perfusion, ventilation and functional residual capacity of an apical field and a basal field of each lung were measured. The results agreed closely with those obtained in healthy adults, studied with the same technique.The reproducibility of the results on one and the same occasion was high as judged from duplicate determinations.Regional lung function in relation to regional functional residual capacity (indices of ventilation and perfusion) and the quotients of ventilation to perfusion of the lung fields were also calculated and were compared with the same measurements in adults. Concerning the perfusion indices for the different lung fields certain differences were found between the two groups of subjects.As the normal range of the different radiospirometric measurements was small the method seems suitable for detecting regional abnormalities in children with lung disease.
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