Abstract
Uranium is one of the most studied actinoids, widely used in the nuclear industry, and can accumulate in drinking water, soil, plants, and calcium-containing body tissues. The purpose of the work was to investigate the presence of uranium isotopes U-235 and U-238 in the composition of kidney stones of patients with urolithiasis living in the Kharkiv region. The content of U-235 and U-238 was investigated in samples of kidney stones obtained as a result of minimally invasive surgical interventions for urolithiasis in 57 patients, residents of the Kharkiv region, using gamma activation analysis on a linear electron accelerator. According to the results of our research U-235 and U-238 were detected in 13 (27%) samples of calcium-containing kidney stones, the mineral composition of which was represented by calcium oxalate monohydrate (wevellite), calcium oxalate dihydrate (weddellite) and phosphate-calcium compounds (apatite, hydroxyapatite, fluorapatite, carbonateapatite). The content of the above-mentioned isotopes in the composition of kidney stones was equal to ~ 1 ppm (mkg/g). We concluded that timely treatment of urolithiasis will help minimize the toxic effect of uranium on kidney structures. Keywords: uranium, Kharkiv region, uroliths.
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