Abstract
Retinal expiants from mice at postnatal days 2–15 were three-dimensionally cultured in collagen gel. The regeneration of neuntes from the expiants was investigated at each stage after birth. The expiants from the central region in the retina could not regenerate neuntes after postnatal day 9, but those from peripheral regions expressed such ability until postnatal day 12. This regional difference in the disappearance stages of retinal regenerative capability coincides with that of retinal maturation.
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