Regiochemical Aspects of the Platinum Oxide Catalyzed Hydrosilylation of Alkynes.

Abstract

The platinum-catalyzed hydrosilylation of unsymmetri- cal substituted arylalkynes with various hydrosilanes was investi- gated and the reaction selectivity of various para-substituted substrates was compared with that of their corresponding ortho- substituted derivatives. We showed that heterogeneous platinum oxide is a very efficient catalyst for such hydrosilylations and that H-Si bond addition proceeds in a stereoselective cis-fashion. The regioselectivity was found to be under the control of the ortho-sub- stituent rather than due to the nature of the platinum catalyst. Aryl- alkynes with an ortho-substituent provided predominantly to exclusively a-selectivity, regardless of the electronic nature of the substituent. The precise contributions of steric, electronic, and co- ordinative factors controlling the regioselectivity of the H-Si bond addition are discussed.