Abstract
Large amounts (250 liters) of dialysate fluid are needed for dialysis of patients with chronic kidney diseases. A reduction of these amounts is obtainable by regeneration. With the Redy system, in which urea is decomposed by the enzyme urease, only 5.5 liters of dialysate is used. Other systems depending solely on sorption of urea still need excessive amounts of sorbents and no alternative, in the form of stable chemical binding, is available. If, therefore, further reduction of dialysate volume is desired, the problem of urea removal must be solved.
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