Abstract

One of the most important indications for guided tissue regeneration (GTR) treatment is class II furcation lesion. However, periodontal regeneration of this type of defect, although possible, is not considered totally predictable, especially in terms of complete bone fill. Many factors may account for variability in the response to regenerative therapy in class II furcation. The purpose of this review is to assess the prognostic significance of factors related to the patient (smoking, stress, diabetes mellitus, acquired immunodeficiency syndrome and other acute and debilitating diseases, and the presence of multiple deep periodontal pockets), local factors (furcal anatomy, defect morphology, thickness of gingival tissue and tooth mobility), surgical treatment (infection control, bone replacement grafts combined with barriers or GTR alone, type of barrier and surgical technique), and postoperative period (plaque control, membrane exposure, membrane retrieval and a regular supportive periodontal care program) for successful of GTR in class II furcations.

Highlights

  • The ultimate objective of periodontal therapy is to regenerate tissues lost as a consequence of periodontal disease

  • Histological and clinical studies have reported the potential of guided tissue regeneration (GTR) to regenerate alveolar bone, cementum and the periodontal ligament [1,2,3,4,5,6,7,8,9,10]

  • In GTR, a barrier is inserted between the root surface and the gingival tissues to inhibit the apical migration of the epithelium and gingival connective tissue of the flap, allowing the granulation tissue derived from the periodontal ligament and osseous tissues to repopulate the space adjacent to the denuded root surface

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Summary

Furcation regeneration

One of the most important indications for guided tissue regeneration (GTR) treatment is class II furcation lesion. Periodontal regeneration of this type of defect, possible, is not considered totally predictable, especially in terms of complete bone fill. The purpose of this review is to assess the prognostic significance of factors related to the patient (smoking, stress, diabetes mellitus, acquired immunodeficiency syndrome and other acute and debilitating diseases, and the presence of multiple deep periodontal pockets), local factors (furcal anatomy, defect morphology, thickness of gingival tissue and tooth mobility), surgical treatment (infection control, bone replacement grafts combined with barriers or GTR alone, type of barrier and surgical technique), and postoperative period (plaque control, membrane exposure, membrane retrieval and a regular supportive periodontal care program) for successful of GTR in class II furcations

INTRODUCTION
PATIENT FACTORS INFLUENCING SUCCESSFUL REGENERATION
LOCAL FACTORS INFLUENCING SUCCESSFUL REGENERATION
Furcal Anatomy
Defect Morphology
Thickness of Gingival Tissue
Tooth Mobility
SURGICAL FACTORS INFLUENCING SUCCESSFUL REGENERATION
POSTOPERATIVE FACTORS INFLUENCING SUCCESSFUL REGENERATION
Findings
CONCLUSIONS
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