Refractivity and polarizability of mixtures of L-histidine–metformin hydrochloride–water at 30°C

Abstract

The molar refractivity and polarizability of mixtures of L-histidine (0.01–0.11 mol L–1)–metformin hydrochloride (0.03, 0.05, 0.07 mol L–1)–water were calculated from density and refractive index data at 30°C. Enhancement in the polarizability has been observed with increase in L-histidine concentration as well as metformin hydrochloride content in the solution. The molar refractivity and polarizability of solutions increased appreciably after 0.09 mol L–1 L-histidine in each aqueous solution.