Abstract
The regulation of kidney function by both volume and osmotic pressure of the blood involves the ADH mechanism. When the two reflex mechanisms compete, the response of the kidney depends on the magnitude of the blood volume. If blood volume is reduced even to a very slight degree, volume control supervenes and water is retained in excess of salt. In the control of volume the afferent impulses from the baroreceptor zones of the circulation play an important role. Since these receptors are not only sensitive to the magnitude of bloodvolume, but also to changes in respiration and cardiac activity it is suggested that volume control is only part of a more complicated mechanism for the defense of an adequate cardiac performance.
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