Abstract

Lowering of [Ca 2−] 0 induces epileptiform activity in hippocampal area CA1, characterized by slow negative field potentials with superimposed trains of population spikes and by rises in [K +] 0. In dentate gyrus slow positive field potentials occur simultaneously with the activity in area CA1. The accompanying small rises in [K +] 0 may stem from spatial K + redistribution through glial cells from area CA1.

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