Abstract
Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease with an increasing prevalence and affects quality of life. Daily insulin replacement therapy is not a radical treatment. With the progress of the disease course, it is often accompanied by a variety of complications and has a high rate of disability and mortality.Many breakthroughs have been made in the prevention and treatment of type 1 diabetes through immune intervention, but clinical trials that have always failed to achieve the desired results have led scientists to rethink where immunotherapy should go in the future. Key words: Diabetes mellitus, type 1; Immunotherapy
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