Reflecting on the Influence of the Current State of Sample Preparation on GC, Part 2: Techniques

Abstract

Recently, we examined major trends in sample preparation and how they relate to gas chromatography (GC), based on a 2023 user survey by LCGC International. In Part 2 of LCGC’s survey of sample preparation users, the prevalence of sample preparation techniques, from the most common, such as weighing, to the most complex, such as online extractions, was discussed. In this installment, we examine trends in the use of sample preparation techniques through the lens of instrumental analysis by gas chromatography (GC) and GC–mass spectrometry (GC–MS). We see that, although common and classical techniques, such as filtration and centrifugation, are still generally the most widely used, newer techniques that allow automation, simplification of analysis steps, and green analysis are gaining traction.