Abstract

Reflectance confocal microscopy (RCM) provides cellular-level insights into cutaneous pathology in vivo and is used to guide both diagnosis and management. The COVID-19 vaccine is the first messenger RNA vaccine in widespread use. Because a variety of cutaneous reactions associated with the COVID-19 vaccination have been reported,1 there may be value in identifying characteristic cellular features using RCM following vaccination. In this study, we used RCM to observe changes in the skin following COVID-19 vaccination.

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