Refining the TEACHH Model: Towards Improved Clinical Utility in the Modern Era

Abstract

128Background: The TEACHH model was previously developed to predict life expectancy in patients with metastatic cancer receiving palliative radiation. However, the model was developed prior to the immunotherapy era and limited in its clinical utility due to broad ranges of survival in each prognostic group. The aim of this project is to refine the TEACHH model to improve its clinical utility in a modern cohort. Methods: We retrospectively reviewed the charts of patients seen in consultation for palliative radiation at two tertiary centers and 4 community satellite practices from 7/1/2015 – 12/31/2016. Cox proportional hazards regression was used to construct a prediction model for overall survival (OS), with a goal of predicting the probability of surviving to the clinically relevant timepoints of 2 months, 6 months, and 1 year. The model was stratified by consult location (tertiary vs. community). Results: A total of 744 patients were included in this analysis. The final model included: 1) Gender (Male H...