Abstract

Refining imaging tools to detect advanced fibrosis: could liver surface nodularity address an unmet need in the NAFLD epidemic?

Highlights

  • In this retrospective cohort study at a tertiary care center in France, patients who underwent liver biopsy and received MRI as part of their clinical workup within 3 months were

  • Data on 142 patients were available and 37% of these had advanced fibrosis defined as the histological disease stages F3 and F4

  • The concept to use liver surface nodularity (LSN) to detect advanced liver fibrosis on CT scan has previously successfully shown for hepatic fibrosis of different indications [8], chronic viral hepatitis c [9], and portal hypertension [10]

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Summary

Introduction

In this retrospective cohort study at a tertiary care center in France, patients who underwent liver biopsy and received MRI as part of their clinical workup within 3 months were. 1 Department of Internal Medicine I, University Medical Center of the Johannes Gutenberg-University, Langenbeckstrasse 1, 55131 Mainz, Germany 2 Metabolic Liver Research Program, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany

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