Abstract
Methods Between April and July 2014 we recruited 32 healthy subjects (no known cardiovascular risk factors, no previous history of heart disease), aged between 20 and 80yrs. All of them underwent a cardiovascular magnetic resonance (CMR at 1.5T, n=19; CMR at 3T, n= 13) protocol that included steady state free precession (SSFP) cines for measuring ventricular dimensions and function, TFisp 2D T2 mapping, dipyridamole stress myocardial perfusion study and late gadolinium enhancement study. T2 maps were obtained in three short axis orientations (basal, midventricular and apical). Regional myocardial T2 values were measured in a 16 segment model and global T2 values were also obtained per slice. A multifactorial ANOVA design was used for the statistical analysis.
Highlights
Myocardial T2 mapping has been recently developed that allows for direct measurement of local myocardial T2, overcoming some of the limitations of T2-weighted images
Regional myocardial T2 values were measured in a 16 segment model and global T2 values were obtained per slice
5 subjects had a total of 9 segments (1.7% of total segments) with T2 ≥ 70 ms, one of them was a midanterolateral segment and all others were apical segments
Summary
Myocardial T2 mapping has been recently developed that allows for direct measurement of local myocardial T2, overcoming some of the limitations of T2-weighted images. We aimed to obtain myocardial regional and global T2 values as a reference for normality, using a novel mapping technique both at 1.5T and at 3T
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