Abstract
Correction: Due to an error in loading the metadata, the author Sahisnuta Basnet was omitted. Sahisnuta Basnet was therefore added to the metadata on 9th January 2017. The PDF was correct.Introduction: Reference hematological values in newborns are informative in evaluation of newborns to determine state of health or disease. For a given population, reference values may differ in accordance with various factors such as age, sex, race, diet, drug intake, altitude, socio-economic status and also the method employed for determination of the values. The aim of this study was to establish reference ranges of complete blood count using umbilical cord blood of normal, healthy, full term neonates born in Manipal Teaching Hospital (MTH), Pokhara, Nepal.Material and Method: The study was conducted in 210 full term, healthy newborns delivered in MTH between Jan 2014 to Feb 2015. Cord blood was collected and a complete blood count was obtained using an automated hematology analyzer.Result: Mean hemoglobin was 15.24 ± 1.96 gm/dl and mean red blood cell count was 4.30 ± 0.63 (range 3.05 – 6.36) X 1012/L. Mean white blood cell count was 14.93 ± 4.44 (range 6.10 ± 31.7) X 109/L and platelet count was 226.88 ± 61.28 (range 105 ± 392) X 109/L. There was no significant difference found in hemoglobin, red cell, white cell and platelet counts between males and females in this study.Conclusion: The values obtained from our study provide ranges for some hematological values in healthy newborns of Pokhara Nepal. However, the hematological reference values for Nepalese cord blood needs to be confirmed by larger numbers of samples from different centers of Nepal.J Nepal Paediatr Soc 2016;36(2):160-164.
Highlights
Reference hematological values in newborns are informative in evaluation of newborns to determine state of health or disease
The Complete Blood Count Complete blood count (CBC) parameters varies with age, race, sex, diet, drugs, analytical methods and other various factors and the concept of an universal “normal” value of complete blood count has changed to reference values for a given population[1,2,3]
This means that it is important to carry out studies to establish standard reference values for the local population[3].Complete blood count (CBC) is one of the most commonly carried out investigation when assessing the health status of an individual; is it a simple investigation to carry out, it is relatively fast, cost effective and a reliable indicator of the health of a person[1]
Summary
Reference hematological values in newborns are informative in evaluation of newborns to determine state of health or disease. The Complete Blood Count CBC parameters varies with age, race, sex, diet, drugs, analytical methods and other various factors and the concept of an universal “normal” value of complete blood count has changed to reference values for a given population[1,2,3]. White blood cell (WBC) and platelets are responsible for providing information regarding sepsis and hemostatic status[1] These CBC parameters of newborns are different than that of adults and should be interpreted in their contexts. This study was carried out to establish mean values for CBC in cord blood in our setting and to compare our values with those obtained from other similar studies
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