Abstract

BACKGROUNDReference intervals (RI) for biochemistry laboratory tests are now based on Caucasian rather than Saudi populations. Test parameters may vary because of race, lifestyle, population structure and geographic location.OBJECTIVESTo establish reference intervals for common clinical chemistry laboratory tests for the Saudi population.DESIGNDirect a priori method.SETTINGTertiary care hospital.MATERIALS AND METHODSBlood samples were taken from 625 individuals aged from 2 to 87 years from different geographic areas for 93 biochemistry tests. RIs were established following the International Federation of Clinical Chemistry guideline.MAIN OUTCOME MEASURE(S)Reference values for common biochemistry lab tests.RESULTSNinety-three age- or gender-stratified reference intervals (RIs) based on the Saudi population were established. There were 72 non-partitioned tests. Most of the tests were similar to RIs from manufacturer’s inserts. For some sex hormones (estrogen, luteinizing hormone, follicle-stimulating hormone, progesterone and 17α-Hydroxyprogesterone) only male RIs were established as there were not enough samples to stratify for females based on physiologic status.CONCLUSIONThe RIs are reliable and applicable to a general Saudi population.LIMITATIONSDue to the sample size, RIs were not generated for some sex hormones for females.

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