Abstract
In the Baylis–Hillman reaction of arylaldehydes with methyl vinyl ketone (MVK), we found that, besides the normal Baylis–Hillman adduct 1 , the diadduct 2 can also be formed at the same time and the yield of 2 can reach to 55% if increasing the amount of methyl vinyl ketone. But for ethyl vinyl ketone (EVK), methyl acrylate or acrylonitrile, only the normal Baylis–Hillman adduct 4 , 7 or 8 was obtained, respectively. The substituent's effects and Lewis base effects were also examined and a plausible reaction mechanism was proposed for the formation of 2 .
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have