Abstract
The development of chiral tertiary alcohols via C-C bond formation is constantly under scrutiny due to the valued promise of these intermediates in biologically active and pharmaceutical products. In this continued work on the reductive aldol reaction of allenic esters to ketones, the authors expand the substrate scope. Changing the conditions slightly enhances the regioselectivity significantly over previous results (Tetrahedron Lett. 2006, 47, 1403-1407).
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have