Reductions in glycated apolipoprotein B after bariatric surgery are more closely associated with decreases in glycaemic parameters than changes in LDL-C or total apolipoprotein B

Abstract

Aim: The causal relationship between LDL-C and atherosclerosis is well-established. Previous studies have shown that modifications (oxidation and glycation) of LDL enhance its atherogenic potential. Small dense LDL (sdLDL) is more likely to cause atherosclerosis than buoyant LDL and is more susceptible to glycation. Our aim was to assess the impact of bariatric surgery on glycated apolipoprotein B (glycApoB) and understand the factors influencing changes in LDL glycation.